Clinico-hematological study of acutemyeloid leukemias

急性髓系白血病的临床血液学研究

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Abstract

CONTEXT: Acute Myeloid leukemia has been of special interest to innumerable workers in the field of cancer research since the blood and haematopoietic tissue can be easily and repeatedly sampled. AIM: To know the relative incidence of Acute myeloid leukemia among the patients referred for complete haemogram at the Department of Pathology, JJMMC, Davangere, India.To study the clinical manifestations and their correlation with various types of acute myeloid leukemia.To study the haematological profiles in acute myeloid leukemia. SETTINGS AND DESIGN: This was a hospital based study conducted at haematology unit, Department of Pathology, JJM Medical College, Davangere, India. MATERIALS AND METHOD: The present study was done during the period of June 2006 to May 2008 at haematology unit department of Pathology, JJM Medical College, Davangere, India. Cases from Chigateri General Hospital, Bapuji Hospital and other private hospitals situated in and around Davangere were included for the study. The case selection was based on the clinical features and supported by laboratory evidence. Bone marrow aspiration was subsequently carried out after obtaining written consent from the patient or the guardian. STATISTICS: The results were expressed in percentage. RESULTS AND CONCLUSION: A total of 1039 patients who were referred to the Department of Haematology out of which 50 patients were diagnosed as Acute Myeloid Leukemia. The present study highlighted that light microscopic features of peripheral smear and bone marrow will still remain mainstay in the diagnosis of acute leukemias.

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