Abstract
BACKGROUND: Cancer is one of the leading causes of mortality in both Mexico and the world, and its incidence continues to rise. Therefore, maintaining up-to-date records of cancer diagnoses at both local and national levels is essential. OBJECTIVE: To analyze malignant neoplasm diagnoses issued by the Pathology Department of a tertiary care hospital in the eastern region of Mexico. MATERIAL AND METHODS: Observational, descriptive study. Cancer diagnoses registered in the Pathology Department of the Hospital de Especialidades, Centro Médico Nacional "General de División Manuel Ávila Camacho," in Puebla, Mexico, were analyzed for the period 2018-2024. RESULTS: Since 2018, a higher number of cases have been observed in women, accounting for 60-64% of total diagnoses. In 2024, the most frequent cancers in the general population were breast, prostate, and skin cancer. Among women, the most common were breast, thyroid/parathyroid, and skin cancers, while in men, prostate, kidney, and skin cancers predominated. A significant increase in diagnoses was recorded in 2024, particularly for breast, thyroid/parathyroid, colorectal, ovarian, kidney, and lung cancer in women, and for prostate, kidney, colorectal, bladder, and thyroid/parathyroid cancer in men. CONCLUSIONS: Access to regional cancer diagnosis data in Mexico is essential for establishing effective strategies for cancer control, early detection, and timely treatment.