Ulcero-granulomatous donovanosis in a HIV positive male

HIV阳性男性患者的溃疡性肉芽肿性杜诺凡病

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Abstract

We report the case of a 29-year-old HIV-positive male on antiretroviral therapy who presented with multiple pinhead-sized papules that progressed into varying-sized ulcers over the penile shaft and glans penis. The patient had a history of both protected and unprotected sexual encounters. Recent contact tracing led to the treatment of some partners, although several could not be traced due to residing in distant areas. The patient had a history of recurrent herpes genitalis for the past 4-5 years, with frequent outbreaks. Laboratory findings revealed a CD4 count of 677 cells/mm(3) and the patient tested negative for hepatitis B, hepatitis C, VDRL, and TPHA. Diagnosis of donovanosis was confirmed by Giemsa staining, which revealed Donovan bodies. This case highlights the importance of early diagnosis, partner tracing, and comprehensive treatment strategies in managing donovanosis in HIV-positive individuals.

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