Abstract
We describe characteristics and results from the DREAM Program, a public health program initiated in Mozambique in 2002 to fight AIDS and other chronic diseases in Sub Saharan Africa. The DREAM Program is currently implemented in 10 countries providing free-of-charges services to over 110,000 patients. DREAM achieved remarkable success in the prevention of mother to child transmission of HIV, in adherence and retention support, in viral load monitoring. Among the challenges: the limited therapeutic options for people living with HIV experiencing virological failure and limited access to resistance tests.