Abstract
Sexually transmitted infections (STIs) have a profound effect on sexual and reproductive health, with an estimated 374 million new infections reported globally in 2020. Most STI cases are likely to be presented at primary care clinics, making it crucial for primary care doctors to possess a strong understanding of STIs. Effective management of these infections relies on timely and accurate diagnosis, evidence-based treatment and comprehensive prevention strategies. The Malaysian Guidelines for the Management of Sexually Transmitted Infections Fifth Edition 2024 highlight the importance of treatment, prevention strategies and diagnostic recommendations, underscoring the role of primary care in addressing STIs effectively.