Abstract
OBJECTIVE: To present a case of metastatic endometrial carcinosarcoma (ECS) with a long-term complete response to chemotherapy using a paclitaxel and carboplatin regimen. CASE REPORT: A 47-year-old premenopausal woman was diagnosed with a large, advanced intrauterine tumor. She underwent a total abdominal hysterectomy with bilateral salpingo-oophorectomy. Pathological assessment revealed a uterine mass with mesenchymal and epithelial components consistent with ECS, while the right ovarian tumor was identified as serous papillary carcinoma. The patient experienced a prolonged postoperative recovery period lasting 3 months. Staging workup later revealed recurrence of adnexal and pulmonary lesions, indicating metastasis. The patient received 6 cycles of postoperative chemotherapy consisting of paclitaxel and carboplatin, achieving complete remission that has persisted for 3 years since the initial diagnosis. CONCLUSIONS: This case highlights the efficacy of postoperative chemotherapy using paclitaxel and carboplatin in the successful treatment of metastatic ECS.