TB co-infection and associated factors among HIV patients attending highly active antiretroviral therapy in Saint Peter's TB Specialized Hospital, Ethiopia: a five years retrospective study

埃塞俄比亚圣彼得结核病专科医院接受高效抗逆转录病毒治疗的HIV感染者合并结核病感染及其相关因素:一项为期五年的回顾性研究

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Abstract

BACKGROUND: TB and HIV are the two widely distributed and successful microbial diseases which impose public health problems globally. OBJECTIVES: The study aimed to determine the prevalence and associated factors of TB among people living with HIV (PLHIV). METHODS: A retrospective study was conducted among PLHIV at Saint Peter's TB Specialized Hospital (SPTSH). Study participants were selected by random sampling technique. Logistic regression analyses were employed to determine the associations between dependent and independent variables. P ≤ 0.05 was taken as statistically significant. RESULTS: The prevalence of TB among PLHIV in the entire study population was 24.6%. The proportion of pulmonary TB (PTB), disseminated TB (DTB) and extra pulmonary TB (EPTB), were 49 (57.6%), 9 (10.6%) and 27 (31.8%), respectively. Logistic regression analysis showed that PLHIV who are non-adhered to ART (AOR = 51.6, 95% CI 24.18 - 387), HAART duration of > 35 months (AOR = 0.39, 95% CI 0.198 - 2.10) and WHO clinical stage IV (AOR = 40.14, 95% CI15.14 - 106.44), were significantly associated with TB/HIV co-infection. CONCLUSIONS: TB co-infection is the major public health issue of PLHIV. Special emphasis is required to reduce the incidence of TB/HIV associated morbidity and mortality among PLHIV.

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