Abstract
OBJECTIVES: This study offers valuable insights into the research hotspots and trends related to ovarian hyperstimulation syndrome (OHSS). By systematically analyzing articles published on the subject up to July 15, 2024, it provides significant perspectives for future research endeavors. METHODS: A literature search was executed utilizing the Web of Science core database to retrieve relevant records, with case reports subsequently reassigned to a separate file. During the analysis phase, countries, institutions, authors, journals, references, and keywords underwent thorough examination using tools such as VOSviewer v1.6.10, CiteSpace, R package, and Microsoft Excel 2021. RESULTS: From the inception of the database to July 15, 2024, a total of 1125 articles were retrieved, including 255 case reports, with a citation count of 23,768. The top 5 countries with the highest article counts were China, the USA, Ireland, the United Kingdom, and Spain. In terms of institutions, Tel Aviv University, Zhengzhou University, Aristotle University of Thessaloniki, Cairo University, and Free University of Brussels were the leading contributors, with Tel Aviv University having the highest number of published articles. Keywords were systematically classified into 4 clusters within the coverage keyword network: diagnosis and clinical manifestations; risk factors and pathogenesis; prevention and treatment; and prognosis and complications. The case reports primarily focused on patients with clinical manifestations of pleural and abdominal fluid accumulation, venous thrombosis, and, in some cases, fatal outcomes. CONCLUSION: The present study conducts a bibliometric analysis of OHSS case reports to understand its prevalence and trends. The study highlights the shift towards advanced assisted reproduction technologies and prophylactic medication as research hotspots, offering valuable guidance for future OHSS research.