Abstract
INTRODUCTION: Complete ectogenesis through artificial womb technology (AWT) would enable fertilization, embryonic development, and fetal development outside of the human body. In 2004, Canada's Assisted Human Reproduction Act established a 14-day legal limit on the in vitro cultivation of human embryos, stymying the domestic development of AWT. Given recent scientific advancements, we aimed to explore Canadians' perspectives on the 14-day rule and AWT development. METHODS: In September 2020-February 2021, we conducted an online English-French survey and semi-structured in-depth interviews with a subset of respondents to solicit Canadian citizens' perspectives on AWT. We audio-recorded and transcribed the telephone/Zoom/Skype interviews and used ATLAS.ti to manage our data. We analyzed survey data using descriptive statistics and interviews for content and themes using inductive and deductive techniques. RESULTS: We received 343 completed surveys and conducted 41 interviews. Although overall knowledge of AWT, in general, and the 14-day rule, in particular, was limited, our participants felt that AWT had the potential to improve lives. Participants also perceived the 14-day rule as an outdated limitation on technological progress and a barrier to AWT development. Participants suggested revisiting the legislation and emphasized centering science, technology, and medicine in any update. DISCUSSION: In 2021, the International Society for Stem Cell Research released updated guidelines which recommended relaxing the 14-day rule, depending on the research objectives. Given the changing domestic and international landscape, Canadian policymakers should revisit the 14-day rule limit imposed by the Assisted Human Reproduction Act and seek input from Canadians when embarking on this reform process.