The pericapsular nerve group (PENG) block versus placebo for postoperative analgesia in elective total hip arthroplasty: Study protocol for a multicenter blinded randomized controlled trial

择期全髋关节置换术后镇痛中,关节囊周围神经阻滞(PENG阻滞)与安慰剂的比较:一项多中心、盲法、随机对照试验的研究方案

阅读:4

Abstract

BackgroundThe pericapsular nerve group (PENG) block is a novel motor-sparing regional technique for hip analgesia. We hypothesized that in patients undergoing hip arthroplasty, the PENG block is more effective in reducing postoperative pain than placebo.MethodsIn this multicenter, double-blind, randomized controlled trial, patients undergoing total hip arthroplasty received spinal anesthesia and local infiltration analgesia, along with either a PENG block or a sham block. The primary outcome was dynamic pain score (numeric rating scale 0-10) measured 3 h postoperatively on day 0. Secondary outcomes included quadriceps strength, pain scores on postoperative day 1, opioid consumption, complications, length of hospital stay, and patient-reported outcome measures.DiscussionThis is the protocol of our trial in which recruitment and data collection were conducted between 28 June 2021 and 8 November 2021. The results can be found in our published work.Trial registration: Ethics approval was obtained from the Southern Area Local Health Network before recruiting the first patient. This trial was prospectively registered prior to initiation on 5 December 2020; URL: https://www.trialregister.nl/trial/9147. The study adhered to the Consolidated Standards of Reporting Trials guidelines and its extension for reporting patient-reported outcomes.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。