Abstract
PURPOSE: Patient reported outcome measures (PROMs) are key tools for monitoring and evaluating treatment effectiveness in people with bronchiectasis. However, most are developed for Anglophone contexts, limiting their applicability to non-English-speaking populations. This systematic review aimed to evaluate the measurement properties of PROMs for Spanish-speaking individuals with bronchiectasis. METHODS: A search of major databases was conducted up to August 2024, targeting studies that assessed the measurement properties (validity, reliability, and responsiveness) of any PROMs available for Spanish-speaking adults with bronchiectasis. The methodological quality of the included studies, as well as the quality of the measurement properties was evaluated according to the COSMIN (Consensus-Based Standards for the Selection of Health Status Measurement Instruments) guidelines. RESULTS: Of 3752 articles, four studies were included. The PROMs were the Leicester Cough Questionnaire (LCQ), Quality of Life Questionnaire for Bronchiectasis (QoL-B), COPD Assessment Test (CAT), and St. George's Respiratory Questionnaire (SGRQ).Content validity was rated as sufficient with low or very low-quality evidence. Structural validity was assessed only for the SGRQ, rated inadequate with very low evidence. Cross-cultural validity could not be evaluated. Convergent validity was sufficient for all PROMs, highest for LCQ and QoL-B. Internal consistency was indeterminate across PROMs, though limited by lack of structural validity. Test-retest reliability was high for LCQ and moderate for QoL-B and CAT. Responsiveness was sufficient for all three PROMs assessed, with evidence quality from very low to moderate. CONCLUSION: Few PROMs exist for Spanish-speaking adults with bronchiectasis. Content, structural and cultural validity, and responsiveness are the least studied properties, limiting treatment monitoring and assessment. REGISTRATION: PROSPERO International register of systematic reviews, CRD42023388173.