[Effect of TVT-Abbrevo in the treatment of female stress urinary incontinence]

[TVT-Abbrevo治疗女性压力性尿失禁的效果]

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Abstract

OBJECTIVE: To evaluate the efficacy of tension-free vaginal tape-Abbrevo (TVT-Abbrevo, TVT-A) in the treatment of female stress urinary incontinence (SUI). METHODS: A retrospective analysis was conducted on patients who underwent TVT-A surgery for SUI in the Department of Obstetrics and Gynecology of Peking University First Hospital from April 2014 to December 2021. Perioperative data were collected, and various questionnaire scores were obtained from the patients before and after the operation, including the International Consultation on Incontinence questionnaire-short form (ICI-Q-SF), the pelvic organ prolapse/urinary incontinence sexual questionnaire-12 (PISQ-12), and the incontinence quality of life questionnaire (I-QOL). A 1-hour pad test was also performed. The efficacy of TVT-A and its impact on the patients' postoperative quality of life and sexual life were analyzed. RESULTS: In this comprehensive study, a total of 130 patients with SUI underwent TVT-A, among whom 111 patients completed the follow-up. The median age of the patients was 60 (51, 66) years, and the median follow-up time was 58.5 (15-105) months. Among the 111 patients, for the 10 patients who solely received TVT-A, the operative duration was (32.25±8.75) min, and the blood loss volume was (12.75±8.48) mL. No intraoperative complications occurred in the 111 patients. Among the postoperative complications, groin pain (8 cases, 7.2%) was the most common, followed by new-onset urinary frequency and urgency (11 cases, 9.9%) and urinary tract infection (4 cases, 3.6%). There were no cases of dysuria, sling erosion, or persistent groin pain. Subjectively, 106 cases (95.5%) were cured and 5 cases (4.5%) were relieved; Objectively, 109 cases (98.2%) were cured and 2 cases (1.8%) were relieved. The ICI-Q-SF scores before and after the operation were 16.00 (11.00, 19.00) and 0.00 (0.00, 5.00), respectively; the PISQ-12 scores were (11.49±3.86) and (13.91±3.96), respectively; and the total I-QOL scores (involving behavioral limitations, psychological impact, and social impairment) were (84.19±15.36) and (106.36±8.93), respectively. All scores improved significantly after the operation compared with those before the operation (P < 0.05). CONCLUSION: TVT-A has fewer intraoperative and postoperative complications, and it has a good therapeutic effect on female SUI. Compared with TVT-obturator, the incidence of groin pain after surgery is lower, which can significantly improve the quality of life and sexual life of the patients.

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