Effect of chronic stress on human endocrine function: A biomarker-based study

慢性应激对人体内分泌功能的影响:一项基于生物标志物的研究

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Abstract

The impact of chronic stress on endocrine function, particularly its effects on cortisol, thyroid hormones, and sex hormones is of interest. The study employed a cross-sectional design, involving 120 participants (aged 18-60) exposed to chronic stress for 6 months or longer. Elevated cortisol levels and disruptions in thyroid and reproductive hormones were observed, particularly in those experiencing high stress. Data show the potential of biomarkers like thyroid-stimulating hormone (TSH) for monitoring stress-related endocrine dysfunctions. Thus, we show the significant role of chronic stress in hormone dysregulation and its associated health risks. The study offers insights into early detection and therapeutic strategies for stress-related health issues.

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