Abstract
Background Women in the Caribbean region experience significant health disparities shaped by intersecting medical and socioeconomic challenges. High rates of obesity, diabetes, and maternal mortality have been observed alongside persistent inequalities in development, employment, and food access. This study aimed to assess gender-based disparities in obesity, diabetes, reproductive health, and socioeconomic conditions across Caribbean countries, comparing outcomes to North America to identify structural drivers of women's health inequities. Methods We analyzed regional and gender-based trends in health and social outcomes across up to 30 Caribbean countries. Publicly available data from 2019 to 2022 were compiled to assess noncommunicable disease prevalence, reproductive health indicators, and key economic metrics. Caribbean nations were compared to the United States and Canada to contextualize findings. Results Women in the Caribbean had higher obesity prevalence and a greater proportion of diabetes-related deaths compared to men. The region also reported elevated maternal and infant mortality, lower inequality-adjusted development scores, and wider gender gaps in unemployment. Food insecurity affected more than 40% of the population in several countries. Adolescent fertility and mortality rates were also higher in the Caribbean than in North America. Multivariate analyses revealed strong associations between chronic disease outcomes and structural indicators such as healthcare access and economic inequality. Conclusion Caribbean women face compounding health risks driven by overlapping medical, economic, and social vulnerabilities. These disparities highlight the need for coordinated regional strategies that go beyond behavioral health to address the broader structural determinants of health and gender equity.