Abstract
BACKGROUND: Dystrophic calcification affecting cardiac structures secondary to hyperadrenocorticism (HAC) is rare in dogs. This case report describes the clinical, imaging, surgical, and pathological findings of a 9-year-old spayed female Maltese dog with severe mitral regurgitation and HAC-related systemic calcification presenting as an intracardiac calcified mass. CASE PRESENTATION: Severe mitral valve thickening and a mobile hyperechoic mass attached to the chordae tendineae were detected on echocardiography. Mitral valvuloplasty was performed, and the calcified mass was excised. Histopathology confirmed a non-neoplastic calcified lesion. Computed tomography revealed extensive calcification in various tissues. The dog developed postoperative aspiration pneumonia and died on postoperative day 2. CONCLUSIONS: This case highlights the potential for intracardiac dystrophic calcification in dogs with HAC and severe mitral valve disease.