Abstract
BACKGROUND: Self-efficacy and knowledge of various types of decision-makers concerning the Human Papillomavirus (HPV) vaccine can play an essential role in the acceptance of the vaccine in women. This study sought to investigate the self-efficacy and knowledge regarding the HPV vaccine among different decision-makers, encompassing self-decision makers (SDM), assisted-decision makers (ADM), and helping-decision makers (HDM). METHODS: This cross-sectional survey was conducted in Jakarta, Indonesia, from May 13th to June 15th, 2023, involving 441 females distributed among three decision-making groups, each comprising 147 participants. Inclusion criteria were not receiving an HPV vaccination and being proficient in Bahasa Indonesia. Specific criteria were women aged 18-26 for SDM, sexually inexperienced female adolescents aged 9-17 for ADM, and mothers of eligible female adolescents for HDM. Participants completed questionnaires on self-efficacy and knowledge of HPV and cervical cancer. The Kruskal-Wallis test and Dunn's post hoc test (P<0.05) were used to analyze the data performed in SPSS 26 software. RESULTS: Most respondents were employed (224, 50.8%), were of low socioeconomic status (271, 61.5%), and had medium knowledge (278, 63%) and medium self-efficacy (190, 43.1%). The HDM and SDM groups demonstrated the lowest and highest knowledge scores, respectively, across all domains compared to the other groups, encompassing knowledge about HPV infection, cervical cancer, and HPV vaccination. The median score for self-efficacy in the SDM and HDM groups was the highest and lowest among the different types, respectively. The median of self-efficacy and knowledge showed statistically significant differences among decision-making groups (P<0.001). CONCLUSION: This study revealed a significant difference between diverse decision-making groups and knowledge and self-efficacy. Educational interventions focusing on various types of decision-maker groups are recommended.