P300 auditory evoked potential latency in elderly

老年人P300听觉诱发电位潜伏期

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作者:Maria José Santos Cóser, Pedro Luis Cóser, Fleming Salvador Pedroso, Rafaele Rigon, Elenara Cioqueta

Aim

To estimate the effect of age on P300 latency in a group of elderly.

Conclusion

The P300 latency increases with age at a rate of 2.85 ms per year between the ages of 60 and 74 years.

Methods

We studied 62 elderly patients with pure tone thresholds up to 40 dB HL at the frequencies of 1000 and 2000 Hz, divided into groups according to age (60-64, 65-69 and 70-74 years). Were assessed by the P300 latency in response to the rare stimulus of 2000 Hz and 1000 Hz frequencies, both in the intensity of 80 dB HL. Study design: clinical, cross-sectional observational individual compared prospective.

Results

The latency in Group 60 was 337.26 ms (SD 11.31) in Group 65 was 351.86 ms (SD 29.05) and in Group 70 it was 370.19 ms (SD 23.40). The linear regression of the values of P300 latency showed an increase of 2.85 ms per year of age. The statistical analysis showed that the results were significant.

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