Summary of the best evidence for non-pharmacological interventions for dyslipidemia in patients with coronary heart disease

冠心病患者血脂异常非药物干预最佳证据总结

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Abstract

OBJECTIVE: Retrieve, evaluate, and summarize evidence from domestic and international sources regarding non-pharmacological interventions for dyslipidemia in patients with coronary heart disease (CHD), providing reference for clinical practice. METHODS: Following the "6S" evidence pyramid model, a systematic search was conducted for literature on non-pharmacological interventions for dyslipidemia in CHD patients, both domestically and internationally, covering the period from January 2014 to December 2025. Two researchers independently screened and evaluated the studies for inclusion, after which the evidence was synthesized. RESULTS: A total of 31 studies were ultimately included, comprising 15 English-language publications and 16 Chinese-language publications. Thirty-one evidence points were summarized, covering seven evidence themes: multidisciplinary team formation, assessment, lipid-lowering targets, lifestyle modification, non-pharmacological traditional Chinese medicine (TCM) interventions, health education, and follow-up management. CONCLUSION: This study provides a comprehensive summary of the best available evidence on non-pharmacological interventions for dyslipidemia in patients with CHD. The findings can serve as a valuable reference for clinical practitioners, enabling healthcare professionals to develop personalized intervention plans based on the lipid profiles and specific needs of CHD patients.

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