Abstract
Preterm birth is a major global health concern associated with high morbidity and mortality rates, along with long-term neurodevelopmental impairments. Developmental supportive care (DSC) plays a crucial role in optimizing neurodevelopmental outcomes in these vulnerable neonates. This study aimed to develop, validate, and assess the feasibility of a nurse-led developmental intervention package (NLDIP). A Medical Research Council (MRC) framework was used to develop and validate the NLDIP. The NLDIP was designed based on a comprehensive scoping review, expert consultations, and practical feasibility assessments in a neonatal intensive care unit (NICU). Validation was conducted through single-round Delphi technique with expert reviews from different fields. The content validity index value was 0.9 and a dry run was performed to assess compliance and feasibility. The NLDIP was systematically developed and validated, comprising three key components: standard DSC, age-appropriate multisensory stimulation (MSS) during hospitalization, and continued MSS at home. The findings demonstrate that the NLDIP is a valid, feasible, and well-structured intervention which can be effectively implemented by nurses in an integrated way to enhance the neurodevelopmental outcomes of preterm infants.