Metabolic associated steatotic liver disease in Qatar: Analysis of dietary patterns and nutrient intake

卡塔尔代谢相关性脂肪肝疾病:饮食模式和营养摄入分析

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Abstract

BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common and increasingly prevalent condition in the Middle East, but its determinants in the region are underexplored. Diet and lifestyle are known to significantly influence MASLD progression. AIM: To assess energy and nutrient intake among MASLD patients living in Qatar and evaluate their dietary patterns. METHODS: Using a cross-sectional design, 94 Arab patients with MASLD, aged ≥ 18 years, living in Qatar were studied. MASLD was diagnosed using ultrasonography, fibro scan, or elastography. Sociodemographic information was collected using a self-administered questionnaire. Dietary intake was assessed through three 24-hour recalls and a qualitative food frequency questionnaire. Energy, macro-, and micronutrient intake were analyzed using Elizabeth Stewart Hands and Associates Food Processor(®) Nutrition Analysis software. Statistical analyses, including factor loadings were performed using STATA 18. RESULTS: Compared to recommended dietary allowance, MASLD patients had high intakes of fat, saturated fat, and cholesterol. They also showed reduced intakes of vitamin K in men, and vitamins E and A (retinol), calcium and magnesium in both genders, while selenium and sodium intakes were higher than recommendations. Three dietary patterns were identified: The 'Traditional Qatari food' pattern, the 'Prudent' pattern, and the 'Fast-food' pattern. However, no significant associations were found between these dietary patterns and body mass index or low-density lipoprotein, using adjusted regression models. CONCLUSION: Findings warrant replication in longitudinal studies and call for dietary interventions to reduce energy density and enhance overall diet quality, including micronutrient intake, for MASLD prevention and management in the region.

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