Abstract
INTRODUCTION: Guillain-Barré syndrome (GBS) is a rare autoimmune disorder of the peripheral nervous system with incidence rates varying across regions. Based on hospital discharge data, this study aimed to analyze the incidence and mortality of GBS in Chile between 2013 and 2019. METHODS: A retrospective review of GBS cases, identified using the ICD-10 code G61.0, was conducted using national hospital discharge records. The incidence rates were calculated annually and adjusted for the population. Demographic and clinical variables, including sex, age, insurance type, and outcomes, were analyzed. RESULTS: A total of 1,696 cases were identified, yielding an annual incidence rate of 1.46 per 100,000 (95% CI: 1.28-2.64). Most cases occurred in males (58.8%), with a mean age of 46.62 years. The mortality rate was 1.7%, and the high survival rate was 98.3%. CONCLUSION: The incidence of GBS in Chile is comparable to the global rates, with a slight male predominance and a high survival rate. Further studies are warranted to explore the potential rurality and climatic factors influencing GBS incidence in Chile.