Abstract
PURPOSE: The objective of this study was to assess the clinical outcomes of surgical management of primary congenital glaucoma (PCG) in a cohort of children treated at Manchester Royal Eye Hospital, Manchester, United Kingdom, over a five-year period. METHODS: This retrospective observational study analysed data from 18 children (31 eyes) diagnosed with PCG between 2019 and 2024. Clinical characteristics, surgical details, intraocular pressure (IOP), optic nerve status, and the need for further surgical intervention were recorded and analysed. RESULTS: The cohort consisted of 14 male and 4 female children, with a mean age at diagnosis of 14 months. Thirteen children had bilateral PCG, and five had unilateral involvement. Presenting features included excessive tearing and increased corneal diameter. The average preoperative IOP was 32 mmHg. Surgical treatment led to significant reductions in both IOP and corneal diameter. Optic disc cupping reversed in most cases. Only two eyes required additional glaucoma surgery. No significant intraoperative complications were recorded. CONCLUSION: Surgical intervention in paediatric glaucoma at a tertiary centre produced favourable anatomical and functional outcomes, with a low reoperation rate. Early diagnosis and timely surgical management remain crucial in preventing vision loss in children with PCG.