Abstract
BACKGROUND: Behçet's disease, first described by Hippocrates and later recognized in modern medicine after Hulusi Behçet's description in 1937, is a complex vasculitis often referred to as the "Silk Road" disease. It is more prevalent in the Middle East and Mediterranean regions, primarily affecting males aged 25-35. CASE PRESENTATION: This study first describes the clinical presentation, timeline, diagnostic evaluation, and therapeutic interventions of one patient. Subsequently, the challenges in diagnosing the disease and selecting treatment strategies are discussed in detail. Finally, the clinical outcomes and treatment effects during the follow-up period are reported. CONCLUSION: This case underscores the necessity of comprehensive diagnosis and integrated treatment for diseases with complex multisystem symptoms. Multidisciplinary collaboration plays a crucial role in the management of such conditions.