Abstract
In recent years, ophthalmology has advanced significantly, thanks to rapid progress in artificial intelligence (AI) technologies. Large language models (LLMs) like ChatGPT have emerged as powerful tools for natural language processing. This paper finally includes 108 studies, and explores LLMs' potential in the next generation of AI in ophthalmology. The results encompass a diverse range of studies in the field of ophthalmology, highlighting the versatile applications of LLMs. Subfields encompass general ophthalmology, retinal diseases, anterior segment diseases, glaucoma, and ophthalmic plastics. Results show LLMs' competence in generating informative and contextually relevant responses, potentially reducing diagnostic errors and improving patient outcomes. Overall, this study highlights LLMs' promising role in shaping AI's future in ophthalmology. By leveraging AI, ophthalmologists can access a wealth of information, enhance diagnostic accuracy, and provide better patient care. Despite challenges, continued AI advancements and ongoing research will pave the way for the next generation of AI-assisted ophthalmic practices.