Abstract
We developed CCorGsDB, a web-based resource integrating mouse and human CNS co-expression networks filtered by circadian biomarkers. We validated the networks using time-series data from sixteen mouse regions and identified a conserved set of 251 orthologs enriched for RNA processing, chromatin regulation, and autism-related phenotypes. The database links CCorGs to disease terms and short-half-life CNS-active drugs with spatially resolved profiles. CCorGsDB is available at https://famed.ufal.br/ccorgs .