Abstract
Three new scalarane-type sesterterpenoids, lendenfeldaranes W-Y (1-3), along with a known analogue, lendenfeldarane D (4), were isolated from a marine sponge identified as Lendenfeldia species. The structures of all isolates were determined based on spectroscopic methods. Scalarane 1 exhibited significant activity in enhancing alkaline phosphatase (ALP) activity.