Abstract
This dataset presents the draft genome of Ochrobactrum anthropi strain Nas42, isolated from metal-contaminated estuarine sediments of the Red River Delta, Vietnam. Genomic DNA was extracted from the isolate and sequenced using the Illumina MiSeq platform, followed by de novo assembly and functional annotation. The generated dataset comprises a 4605,092 bp draft genome assembled into 27 contigs with a GC content of 56.11%, containing 4356 protein-coding sequences. Notably, in silico whole-genome comparison supported its taxonomic assignment to O. anthropi, demonstrating 99.37% Average Nucleotide Identity (ANI) with strain PBO and the absence of IS711 insertion sequences, a genomic feature characteristic of Brucella species but absent in Ochrobactrum. Additionally, the annotated dataset highlights 45 genes associated with metal resistance, including those encoding resistance to cobalt, zinc, cadmium, and copper. This genomic resource can be reused by the scientific community to investigate metal resistance determinants, explore microbial adaptation mechanisms in polluted estuarine environments, and support phylogenomic analyses of the Ochrobactrum-Brucella complex.