Abstract
The morbidity and mortality of gynecological tumors have been increasing globally in recent years. The identification of new biomarkers and drug targets has become an opportunity and challenge in the treatment of these tumor types. In recent years, the role of mitochondrial oxidative phosphorylation in the development of gynecological tumors has attracted attention, and existing studies have shown that complement component 1 Q subcomponent-binding protein (C1QBP) is involved in critical biological processes such as proliferation, migration and invasion of these tumors. However, the specific mechanism and function of C1QBP in gynecological tumors remain unknown and further studies are still needed to reveal its role and clinical application prospects. Therefore, the present review describes the changes and mechanism, such as in the apoptosis and invasion of tumor cells, of C1QBP in cervical, ovarian and endometrial cancer. The present review examines the current research progress on C1QBP in gynecological tumors to provide new ideas and methods for diagnosing and treating this disease.