Association study of the CSN2 gene with milk yield in the Sapera goat

萨佩拉山羊CSN2基因与产奶量的关联研究

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Abstract

OBJECTIVE: This research was conducted to assess the influence of CSN2 exon 7 milk production and the additive and dominance effects. MATERIALS AND METHODS: DNA was isolated from 64 goats that possessed the CSN2 gene and subjected to a polymerase chain reaction and genotyping by Sanger sequencing.Genotype effect can be assessed through analysis of variance and the generalized linear model, which can estimate additive and dominance effects. RESULTS: Dairy traits are greatly influenced by the crucial role played by the CSN2 gene. The influence of SNP g.8946C > T on milk yield (MY) is statistically significant (p < 0.05). Nevertheless, the impact of SNP g.8956G > A on MY is not statistically significant. Furthermore, the MY of Sapera goats is affected by both Parity (p <0.01) and days in milk (p < 0.01). CONCLUSION: The CC genotype demonstrates a higher MY without noticeable additive or dominance effects. Evaluating the SNP g.8946C > T necessitates many samples and phenotypes.

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