Normative Data of Ocular Vestibular Evoked Myogenic Potentials in Response to Chirp Stimulus

对啁啾刺激的眼动前庭诱发肌源性电位的正常值数据

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Abstract

OBJECTIVES: This study aims at comparing the tone-burst (TB) and narrow-band (NB) CE-chirp stimuli in terms of amplitude, latency, and interaural asymmetry ratio (IAR) in ocular vestibular evoked myogenic potentials (oVEMP). MATERIALS AND METHODS: In this prospective study, we enrolled 60 healthy subjects (27 men, 33 women) with a mean age of 25.83 (range, 18-48) years. Otological examination was normal in all the subjects. The subjects did not have any otological disease. All the subjects underwent oVEMP testing. We used 500 Hz TB stimulus and 500 Hz NB CE-chirp stimulus in random order. oVEMP test was performed at 100 dB normalized hearing level. P1 latency, N1 latency, and P1N1 amplitude were measured for each ear and stimulus, and IAR was calculated. RESULTS: Ocular VEMPs were obtained from all the subjects for both the stimuli. P1 and N1 latencies were significantly shorter in chirp stimulus than in TB stimulus for both the sides (p<0.0001). P1 and N1 amplitudes were significantly higher for chirp stimulus than for TB stimulus for both the sides (p<0.0001). There was no significant difference between the ears in IAR between the 2 types of stimuli. CONCLUSION: Narrow-band CE-chirp stimulus is an effective stimulus to evoke oVEMP with higher amplitudes and shortened latencies.

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