Abstract
PURPOSE: Allergic diseases are frequently underdiagnosed in older adults due to overlapping symptoms with other chronic conditions and age-related changes in the immune system. As the elderly population continues to grow, understanding the prevalence and clinical impact of allergic diseases in this group is essential. This study aimed to assess the prevalence of common allergic conditions in individuals aged 65 and older and to examine their associated comorbidities. PATIENTS AND METHODS: We conducted a retrospective chart review of approximately 17,000 patients aged 65 and older who were diagnosed with allergic diseases between January 2020 and December 2023. Data on age, sex, race/ethnicity, specific allergic diagnoses, and comorbid medical conditions were extracted from electronic health records and analyzed descriptively. RESULTS: Allergic rhinitis and asthma were the most prevalent allergic conditions, affecting 51.2% and 50.3% of the study population, respectively. Food allergies were identified in 8.4% of patients, contact dermatitis in 4.5%, and atopic dermatitis in 2.9%. Comorbidities were most frequent among patients with allergic rhinitis and asthma. Hypertension was the most common comorbidity overall, affecting 77.7% of patients with allergic rhinitis and 77.2% with asthma, followed by coronary artery disease. Rates of allergic disease were higher among patients aged 65-75 compared to those over 75, and prevalence was generally higher in women than in men. CONCLUSION: Allergic conditions, particularly allergic rhinitis and asthma, are common in older adults and often coexist with cardiovascular and metabolic comorbidities. These findings underscore the need for increased clinical awareness and tailored diagnostic approaches in elderly populations to avoid missed or delayed diagnoses and to improve management outcomes.