g-C3N5-dots as fluorescence probes prepared by an alkali-assisted hydrothermal method for cell imaging

碱辅助水热法制备 g-C3N5-dots 作为细胞成像荧光探针

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作者:Xiangwang Zeng, Mengke Hou, Pan Zhu, Minyi Yuan, Sitao Ouyang, Qiujun Lu, Chenxi Zhao, Haiyan Wang, Fuyou Du, Guangsheng Zeng, Youyu Zhang

Abstract

Carbon nitride materials have become one of the highly explored carbon-based nanomaterials due to their unique properties. Herein, the novel graphitic carbon nitride quantum dots (g-C3N5-dots) were synthesized using an alkali-assisted hydrothermal method. The proposed strategy was simple, time-saving and the entire synthetic process only takes 60 min. And the prepared g-C3N5-dots showed excellent dispersion and good stability in water. What is more, the g-C3N5-dots displayed bright blue fluorescence with a high quantum yield of 12%. It was found that the g-C3N5-dots exhibited peroxidase-like activity, good biocompatibility and low cytotoxicity and can be successfully applied in cell imaging. The proposed method opens a new and efficient way for the preparation of fluorescent g-C3N5-dots and facilitates g-C3N5-dots for bioimaging and related biological sensing applications.

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