Abstract
Antimicrobial resistance in bacteria has become a major challenge in global public health. Globally, the emergence and rapid spread of carbapenem-resistant Enterobacteriaceae（CRE）pose a significant threat to human health. Patients with hematological malignancies are at a high risk of CRE infection, and the mortality rate of such infections is also relatively high. In these patients, how to diagnose, treat, and prevent CRE infection has become the most difficult issue in bacterial infection. To standardize the diagnosis, treatment plans, and prevention strategies for CRE infection in patients with hematological malignancies in China, hematology and infectious disease experts were invited to discuss and reach a consensus on the epidemiological characteristics of CRE infection, laboratory detection, treatment principles, main therapeutic drugs and dosing regimens, risk factors for CRE infection and colonization, and hospital infection prevention and control.