Hyperspectral Imaging Reveals High Water and Hemoglobin Content at Rest and Decreased Oxygen Levels After Physical Activity at the Residual Limb of Non-Dysvascular Lower Limb Amputees

高光谱成像显示,非血管功能障碍下肢截肢患者的残肢在静息状态下水分和血红蛋白含量较高,而在运动后氧气水平降低。

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Abstract

OBJECTIVE: Skin integrity is one factor determining residual limb health. Oxygen deficiency caused by energy consumption and/or mechanical stress is the most common reason for skin breakdown at the residual limb (RL), limiting physical activity and causing residual limb pain (RLP). This study aims to detect differences in microcirculation at rest (T1) and after walking for 6 min (T2) with a socket prosthesis at different zones at the residual limb (RL) and the corresponding areas at the sound limb (SL). METHODS: Amputation and RLs' demographics as limb circumference (LCF), subcutaneous fat thickness (SCFT) and microcirculatory parameters as tissue oxygenation saturation (StO(2)), near-infrared perfusion index (NIRPI), tissue hemoglobin index (THI) and tissue water index (TWI) were visualized and analyzed at different zones of the SL and RL of ten non-dysvascular major lower limb amputees at T1 and T2 using ((HIS), TIVITA Tissue Diaspective Vision, Germany). RESULTS: LCF and SCFT were lower at the RL than at the SL. A significant reduction of NIRPI after walking was observed at location F2, affecting both limbs. StO(2) decreased significantly from T1 to T2 only at the residual limb at AL, with no corresponding change in the sound limb. DISCUSSION: These findings demonstrate localized exercise-related reductions in oxygenation at the distal RL, whereas microcirculation of the SL remained unchanged. Underlying factors and a possible impact on the overall residual limb health need further investigation.

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