Abstract
Inappropriate antimicrobial use (misuse, overuse, underuse, and abuse), often due to a lack of knowledge, is a major factor driving antimicrobial resistance (AMR). Effective education and awareness programs are crucial for addressing this issue. This paper examines how implementation science can improve AMR education and awareness in the World Health Organization (WHO) African Region. This paper discusses the relevance of implementation science frameworks and practical strategies for adapting AMR initiatives to local contexts. By reviewing the literature and case studies, this paper underscores the need for tailored approaches that reflect the region's unique socio-cultural and healthcare settings. Integrating implementation science into AMR education can promote sustainable behavior change with regard to antimicrobial use, improve healthcare practices, and help combat AMR.