Abstract
A 73-year-old man was hospitalized for intestinal perforation and underwent surgery. Subsequently, he experienced recurrent gastrointestinal bleeding. A second operation revealed invasive mucormycosis—a rare but severe fungal infection of the digestive tract. Typically treated with amphotericin B, mucormycosis often occurs in immunocompromised patients; however, this patient had no history of immunosuppressive therapy or known risk factors. In cases of gastrointestinal bleeding, performing biopsies and cultures during endoscopic examinations when ulcers are detected is recommended to ensure accurate diagnosis. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12879-025-11783-9.