Modeling sparse Rift Valley fever incidence data: a Bayesian perspective on zero-inflated self-exciting and autoregressive models

基于贝叶斯视角的零膨胀自激和自回归模型,对稀疏裂谷热发病率数据进行建模

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Abstract

BACKGROUND: Rift Valley fever (RVF) is a mosquito-borne zoonotic disease for which predictive modeling is often hindered by sparse data, particularly the high frequency of zero counts in both human and livestock surveillance systems. While zero-inflated models are commonly used for sparse data, several temporal count modelling frameworks exist, including less common self-exciting models that assume an initial case increases the likelihood of subsequent cases. METHODS: This study compares three zero-inflated Bayesian models: the negative binomial (ZINB) with autoregressive temporal random effects, the self-exciting negative binomial (SE-NB) and the generalized autoregressive moving average negative binomial (GARMA-NB). The models were evaluated across simulated datasets with varying levels of sparsity. RESULTS: We found that zero-inflation substantially improves predictive performance within specific sparsity thresholds: 29-94.5% (ZINB), 25-93% (SE-NB), and 30-95% (GARMA-NB). Applied to monthly RVF incidence data from northern Kenya (2018-2024), the ZINB model with a three-month rainfall lag provided the most accurate forecasts. CONCLUSION: These findings underscore the importance of zero-inflated negative binomial models and climate-based covariates in enhancing early warning systems for RVF-endemic regions.

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