Abstract
BACKGROUND: Effective glycemic management in type 2 diabetes remains challenging due to limited patient self-management and fragmented care. The National Standardized Metabolic Management Center (MMC)-assisted glycemic control assistant is a novel digital platform that integrates real-time monitoring, education, and treatment adjustment. This study evaluated its impact on biochemical markers and patient behaviors compared with routine care. METHODS: A retrospective study was conducted on 160 patients with type 2 diabetes, including 95 who received MMC-assisted digital management and 65 who received routine care. Key biochemical parametersfasting plasma glucose (FPG), 2-hour postprandial glucose (2hPG), and glycated hemoglobin (HbA1c)were measured using standardized enzymatic assays. Dietary behavior and diabetes self-management were also assessed using validated scales. RESULTS: At baseline, groups were comparable in clinical and behavioral characteristics. After intervention, the MMC group achieved greater improvements: FPG decreased by 10.1% (7.42± 2.43 vs. 8.30± 2.66 mmol/L, P= 0.032), 2hPG by 17.5% (10.23± 3.21 vs. 12.39± 3.50 mmol/L, P < 0 .0 0 1 ), and HbA1c by 9.0% (7.26 ± 2.05 % vs. 7.98± 2.34% , P = 0.041). Significant gains were also observed in dietary behavior and adherence to glucose monitoring, medication, and exercise. CONCLUSIONS: The MMC-assisted glycemic control assistant enhances glycemic control and promotes healthier behaviors in type 2 diabetes. These findings support its clinical utility and highlight the potential for broader integration of digital tools into standardized chronic disease management.