Abstract
Exosomes derived from dendritic cells (dexosomes) induce potent antitumor immune responses in mice. We have shown that the efficacy of dexosome-elicited antitumor immunity relies on the presence of both T- and B-cell dexosome-associated epitopes. Hence, the inclusion of B-cell epitopes in anticancer vaccines is crucial for the success of this immunotherapeutic intervention.