How the devil facial tumor disease escapes host immune responses

魔鬼面部肿瘤疾病如何逃避宿主免疫反应

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Abstract

The devil facial tumor disease (DFTD) is a contagious cancer that has recently emerged among Tasmanian devils, rapidly decimating the population. We have recently discovered that DFTD cells lose the expression MHC molecules on the cell surface, explaining how this tumor avoids recognition by host CD8(+) T cells.

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