Abstract
T(H)9 cells join the ever-growing list of CD4(+) T helper subsets and primarily mediate anti-parasite immune responses. We have recently demonstrated that tumor-specific T(H)9 cells induce a CCL20-CCR6-dependent regulation of DCs while stimulating CD8(+) T cell-mediated antitumor immunity. These findings offer a novel immunotherapeutic strategy against cancer.