Protective role of STING against gliomagenesis: Rational use of STING agonist in anti-glioma immunotherapy

STING在抑制胶质瘤发生中的保护作用:STING激动剂在抗胶质瘤免疫治疗中的合理应用

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Abstract

We recently reported that STING contributes to antiglioma immunity by triggering type I IFN induction in glioma microenvironment. Moreover, intratumoral administration of STING agonist improved the efficacy of peptide vaccination in a mouse glioma model, suggesting the rational use of STING agonists in the immunotherapy of brain tumor.

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