Abstract
OBJECTIVE: This study aimed to investigate the relationship between long working hours and chronic kidney disease (CKD) according to diabetic status. METHODS: Twelve thousand seven hundred three full-time employees without diabetes and 2136 with diabetes were included in this study. Participants were grouped according to working hours: ≤40, 41 to 52, and >52 h/week. Multiple logistic regression was used to evaluate the association between working hours and CKD prevalence. RESULTS: Participants with diabetes who worked 41 to 52 h/week showed 1.85 times higher odds of CKD (95% CI 1.15-2.96; P = 0.0112) compared with those who worked ≤40 h/week after adjusting for covariates. An interaction between diabetes and long working hours was observed (P for interaction = 0.0212) in the model. CONCLUSION: Long working hours are associated with CKD in participants with diabetes. An interaction between long working hours and diabetes leading to CKD development may exist.