Abstract
BACKGROUND: In recent years, inadequate sleep duration has become a prominent concern all over the world, prompting investigations into its potential influences on various health conditions, including kidney disease. This study seeks to explore the association between weekend catch-up sleep (WCS) and kidney disease in American adults. METHODS: A cross-sectional study was performed utilizing data from the National Health and Nutrition Examination Surveys (NHANES) spanning the years 2017-2020. The participants included who were 18 years old or older and clearly awareness of their sleep durations on weekdays and weekends. Sleep durations on weekdays and weekends were ascertained through questionnaires, and WCS was determined as the disparity between weekend and weekday sleep durations. RESULTS: Participants with kidney disease exhibited notable variations in their weekday and weekend sleep durations in comparison to those without. The WCS of more than 2 h, irrespective of comorbidities such as hypertension and diabetes, was significantly linked to a lower prevalence of kidney disease, particularly in individuals who slept 6-8 h on weekdays. Furthermore, it was noted that there exists a non-linear correlation between WCS and the prevalence of kidney disease, with a distinct breakpoint identified at 3.5 h. The WCS of more than 2 h-possibly but not certainly-irrespective of comorbidities such as hypertension and diabetes, was significantly linked to a lower prevalence of kidney disease, particularly in individuals who slept 6-8 h on weekdays. CONCLUSION: This research indicates that among adults with insufficient weekday sleep in the United States, participation in WCS, particularly exceeding 2 h is significantly linked to a decreased prevalence of kidney disease. These results offer new perspectives on the connection between sleep patterns and kidney disease, which could inform preventive measures for this prevalent chronic condition.