Neuroblastoma involving urinary bladder: A rare type of tumor with diagnostic ambiguity

累及膀胱的神经母细胞瘤:一种罕见的、诊断模糊的肿瘤

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Abstract

INTRODUCTION: Neuroblastoma of urinary tract is an extremely rare type of tumor and only a few cases have been reported worldwide. CASE PRESENTATION: We presented an adult case of neuroblastoma involving urinary bladder. Patient was a 24-year-old man with a history of repeated attack of hematuria. Patient underwent cystoscopy and transuretheral resection of bladder tumor. Biopsy result was "Blastema cell (suggestive of neuroblastoma) with immature ganglion cells." Immunohistochemistry workup was continued and neuron-specific enolase and S100 staining were positive. Patient lost to further follow-up visit. CONCLUSION: Although neuroblastoma of skin and peripheral nerve is not a rare disease entity, involvement of deeper structures (especially urinary bladder) is exceptional.

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