Abstract
INTRODUCTION: Bladder diverticulum rarely causes deep vein thrombosis (DVT) due to compression of leg veins. However, only a few cases have been reported to date. In this article, we report the first known case of DVT caused by a giant bladder diverticulum associated with long-term use of antipsychotic medication. CASE PRESENTATION: A male in his 40s with a 20-year history of schizophrenia was admitted to the hospital with complaints of swelling and pain in the left lower extremity. He was diagnosed with drug-induced urinary retention caused by antipsychotics, a giant bladder diverticulum, and DVT. The patient underwent urinary catheter placement and was treated with rivaroxaban. He has limited therapeutic options due to poor adherence to treatment and is currently undergoing intermittent replacement of the urinary catheter. CONCLUSION: Patients taking antipsychotic medications must be aware of the risk of urinary retention and may be unable to choose optimal medical care.