Abstract
BACKGROUND: Inferior vena cava (IVC) thrombosis associated with autosomal dominant polycystic kidney disease (ADPKD), caused by mechanical compression from a large liver or renal cysts, has previously been reported. However, postoperative thrombosis following nephrectomy of the native kidneys has not been described. CASE PRESENTATION: Case 1: A 50-year-old female underwent bilateral native nephrectomy to create space for a kidney allograft. Postoperatively, her D-dimer level was elevated, and contrast-enhanced computed tomography (CECT) revealed an IVC thrombus. Anticoagulation therapy was initiated, and living-donor kidney transplantation was performed eight months later.Case 2: A 46-year-old male developed thrombosis of the IVC and common iliac vein after bilateral native nephrectomy. Anticoagulation therapy was continued for four months, followed by successful living-donor kidney transplantation. CONCLUSION: CECT is desirable for the diagnosis of IVC thrombosis following native nephrectomy in patients with ADPKD.