Abstract
BACKGROUND: Several advanced methods for evaluating wrinkles are currently available, however, with limitations in their application because wrinkle structures change in response to facial expressions and surrounding environments. A Visual Illusion-based image feature enhancement System (VIS) was used to develop a real-time evaluation method. OBJECTIVES: This study expands the VIS application into the wrinkle evaluation method by adjusting VIS to evaluate facial wrinkles, evaluating the age-dependent wrinkles, and validating it for real-time wrinkle evaluation. METHODS: Wrinkles in various Japanese men and women were evaluated using VIS and the current methods. Furthermore, the effectiveness of an eye cream containing niacinamide was evaluated before and after the 4-week treatment. RESULTS: VIS qualitatively detects even fine wrinkles and numerically records them without any special instrument. Moreover, VIS can be applied to moving images, revealing the effectiveness of the antiwrinkle formulation qualitatively and quantitatively even when the subjects are smiling. CONCLUSION: This paper presents an epoch-making wrinkle evaluation method that is qualitative and quantitative, with high sensitivity in real-time and relies solely on digital images without any difficulties. Therefore, these results imply that this method enables the wrinkle evaluation under real-life conditions.