Abstract
BACKGROUND/PURPOSE: Among the characteristics that appear in the epidermis of the skin, erythema is primarily evaluated through qualitative scales, such as visual assessment (VA). However, VA is not ideal because it relies on the experience and skill of dermatologists. In this study, we propose a new evaluation method based on hyperspectral imaging (HSI) to improve the accuracy of erythema diagnosis in clinical settings and investigate the applicability of HSI to skin evaluation. METHODS: For this study, 23 subjects diagnosed with atopic dermatitis were recruited. The inside of the right arm is selected as the target area and photographed using a hyperspectral camera (HS). Subsequently, based on the erythema severity visually assessed by a dermatologist, the severity classification performance of the RGB and HS images is compared. RESULTS: Erythema severity is classified as high when using (i) all reflectances of the entire HSI band and (ii) a combination of color features (R of RGB, a* of CIEL*a*b*) and five selected bands through band selection. However, as the number of features increases, the amount of calculation increases and becomes inefficient; therefore, (ii), which uses only seven features, is considered to perform classification more efficiently than (i), which uses 150 features. CONCLUSION: In conclusion, we demonstrate that HSI can be applied to erythema severity classification, which can further increase the accuracy and reliability of diagnosis when combined with other features observed in erythema. Additionally, the scope of its application can be expanded to various studies related to skin pigmentation.