Heat shock protein 70 upregulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage
格尔德霉素上调热休克蛋白 70 可减轻小鼠脑出血模型中的脑损伤
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作者：Anatol Manaenko, Nancy Fathali, Hank Chen, Hidenori Suzuki, Shammah Williams, John H Zhang, Jiping Tang
Conclusion
Geldanamycin post-treatment is neuroprotective in the mouse model of intracerebral hemorrhage. Geldanamycin administration results in reduction of inflammation, preservation of blood-brain-barrier and amelioration of neurobehavioral deficits after an insult possibly by upregulation of heat shock protein 72.
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